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Does the P-Shot Really Work?

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Sexual performance and confidence are concerns many men quietly struggle with. In the United States, an estimated 30 to 50 million men experience some degree of erectile dysfunction (ED), while others report challenges with sensitivity, stamina, or overall sexual satisfaction. As awareness grows, more men are exploring treatments that aim to improve sexual health without relying solely on medications or surgery.

One option that has gained attention is the Priapus Shot, commonly called the P-Shot. This treatment uses platelet-rich plasma (PRP) drawn from a patient’s own blood with the goal of supporting blood flow and tissue health in the penis.

So, does the P-Shot really work?

The answer depends on the individual. Some men report improvements in erection quality, sensitivity, and confidence, while others notice more subtle changes or no significant difference at all. Outcomes vary based on health, age, and underlying causes of sexual dysfunction.

In this article, we’ll explain how the P-Shot works, what current research and patient experiences suggest, and what to realistically expect if you’re considering this treatment.

What Is the P-Shot?

The P-Shot is a regenerative treatment that uses a patient’s own blood to support sexual function. It is based on PRP therapy, a medical technique widely used in orthopedics, dermatology, and aesthetic medicine to stimulate the body’s natural healing processes.

The name Priapus comes from the Greek god of male virility, reflecting the procedure’s goal of restoring performance and confidence. The P-Shot was developed by Dr. Charles Runels, who also introduced the well-known “vampire facial.” His objective was to apply regenerative science used in skin rejuvenation to men’s sexual health.

By delivering concentrated growth factors directly into targeted penile tissue, the P-Shot aims to support blood flow, tissue repair, and sensitivity over time.

How the P-Shot Procedure Works

The P-Shot procedure follows a structured, clinical process designed to safely deliver platelet-rich plasma to targeted penile tissue.

What Happens During a P-Shot Treatment?

A P-Shot treatment is typically completed in under an hour and follows a standardized clinical process:

  1. Blood collection: A small amount of blood is drawn, similar to a routine lab test.
  2. Plasma separation: The blood is placed in a centrifuge to isolate platelet-rich plasma (PRP), the portion containing growth factors and healing proteins.
  3. PRP preparation: The concentrated PRP is prepared for injection.
  4. Targeted injection: Using a fine, sterile needle, the PRP is injected into specific areas of the penis associated with erectile tissue and sensitivity.

The procedure is minimally invasive, and most patients resume normal daily activities shortly afterward.

As for the P-Shot cost, it varies depending on geographic location, provider experience, and whether additional services (such as consultation, anesthesia, or complementary therapies) are included. Asking your provider for a detailed cost estimate is the best way to understand the full financial scope of treatment.

Priapus Shot Post-Care

After treatment, medical providers typically recommend avoiding sexual activity for one to two days to allow the tissue to recover. Mild swelling, tenderness, or bruising at the injection site may occur and usually resolves within a few days.

Because the P-Shot uses platelet-rich plasma derived from your own blood, the risk of side effects is generally low compared to treatments that introduce synthetic substances or foreign materials. However, as with any injection-based procedure, potential side effects may include temporary discomfort, swelling, bruising, or infection if proper sterile technique is not followed. Serious complications are uncommon when the procedure is performed by a qualified medical professional.

Once injected, PRP begins working beneath the surface by supporting tissue regeneration, collagen production, and improved microcirculation. Over time, these effects may contribute to firmer erections, improved sensitivity, and overall penile tissue health.

P-Shot Benefits Backed by Research and Experience

Another question most men ask before finally committing to the procedure is, “What kind of P-Shot benefits can I realistically expect?” While every individual’s experience can vary, the P-Shot has been reported to offer a wide range of potential benefits besides improved erections:

1. Improved Erectile Function

One of the most common reasons men consider the P-Shot is to improve erectile performance. Since platelet-rich plasma helps repair microvascular tissue and enhance blood circulation, it naturally supports better oxygen and nutrient delivery to the erectile chambers. 

This process encourages stronger, more sustainable erections, sometimes within weeks, with continued improvement over time.

Clinical studies on PRP for erectile dysfunction have shown that this approach may boost penile blood flow and tissue regeneration. 

For men who can’t tolerate or haven’t responded well to oral medications, the P-Shot provides a natural, male regenerative power that supports long-term vascular health and enhances sexual function.

2. Enhanced Sensitivity and Sexual Pleasure

Another frequently cited benefit is heightened penile sensitivity. As PRP promotes tissue repair and improved blood flow, some men report greater sensation and more intense orgasms. This improvement in responsiveness can also translate into renewed confidence and intimacy in their sex life.

3. Better Stamina and Performance

Although not specifically intended to increase endurance, the P-Shot’s circulatory and tissue-repair benefits may contribute to better stamina during sexual activity. Some adult males notice improved control and longer-lasting performance after treatment.

4. Support for Peyronie’s Disease

Emerging research suggests that PRP may help men with Peyronie’s disease. It’s a condition caused by scar tissue that can lead to penile curvature and discomfort. The growth factors in PRP may assist in softening plaques and encouraging healthier tissue remodeling over time.

5. Psychological Confidence

Outside physical results, many patients report a meaningful boost in confidence and self-esteem after this advanced treatment. Improved performance and sensation often lead to reduced anxiety and enhanced overall quality of life.

While the P-Shot is designed to support overall sexual health and performance, some men also notice increased penis length or subtle changes in size or girth. These P-Shot size results tend to be modest and vary by individual, and complement the other functional benefits of the treatment.

Overall, the results can vary. However, the current body of evidence, supported by both clinical research and real-world patient experiences, suggests that the P-Shot may offer gradual, natural improvement rather than an instant fix.

P-Shot Reviews: What Real Patients Say

Looking at P-Shot reviews, experiences range from highly positive to more moderate, which is expected, since outcomes depend on factors like age, health, and injector skill.

Positive Experiences

Many men report noticeable improvements in erection quality, sensitivity, and sexual satisfaction. Most describe the results as natural rather than artificial, with some seeing changes within a few weeks and others experiencing gradual progress over several months.

Moderate Experiences

Some patients notice only modest or gradual changes, such as slight improvements in firmness, stamina, or sensitivity, rather than dramatic results. Medical experts note that the P-Shot tends to work best for men with mild-to-moderate concerns, while more severe ED issues may require additional treatments.

Negative Experiences

Negative P-Shot reviews typically come from men who experience minimal or no noticeable improvement after treatment. This is more common in cases involving severe erectile dysfunction, underlying health conditions, or unrealistic expectations about the results.

Some negative experiences are also linked to differences in provider technique or the misconception that the P-Shot delivers immediate or dramatic changes. Because PRP relies on the body’s natural healing response, results can vary, and the treatment may not be effective for everyone.

In short, the P-Shot is not a “one-and-done” solution. It works best as part of a personalized sexual health plan and customized to an individual’s needs and goals.

So, Does the P-Shot Work for Everyone?

The P-Shot offers men a chance to enhance sexual performance, heighten sensitivity, and regain confidence in the bedroom. While research and patient experiences show encouraging results, individual outcomes can vary depending on factors like age, overall health, circulation, and lifestyle habits.

It’s not a magic solution, but the P-Shot works best when integrated alongside other treatments or healthy lifestyle changes. At InjectCo, we take the time to understand your goals and create a plan tailored to you. 

Curious to see if the P-Shot could make a difference for you? Book a free virtual consultation today and explore how this cutting-edge treatment might help you feel your best.

Frequently Asked Questions

Can the P-Shot help with erectile dysfunction?

Yes, the P-Shot has been reported to improve erectile function in some men. The treatment may help regenerate tissue, improve blood vessel health, and enhance circulation in the penis. While results vary, early studies and patient experiences suggest it can be a helpful option for men with mild-to-moderate erectile dysfunction.

What does a typical P-Shot procedure involve?

During the P-Shot procedure, a small amount of your blood is drawn and processed to isolate platelet-rich plasma. Before the injections, a numbing cream is applied to ensure comfort. The PRP is then carefully injected into targeted areas of the penis to stimulate tissue repair and support improved function. The entire session usually takes under an hour, with minimal downtime and a brief recovery period.

How does the P-Shot use my own blood to improve sexual health?

The P-Shot relies on platelet-rich plasma derived from your own blood, which is rich in growth factors and proteins. When injected, it encourages tissue regeneration, supports the formation of new blood vessels, and improves microcirculation.

Are there any clinical trials supporting the effectiveness of the P-Shot?

Yes, several clinical trials and pilot studies have investigated PRP therapy for erectile dysfunction and penile tissue health. These studies suggest improvements in blood flow, erectile function, and tissue regeneration. However, research is still ongoing, and outcomes can vary depending on individual health factors.

Can the P-Shot increase size or improve blood flow to the penis?

The P-Shot may improve blood flow and support tissue regeneration, which can lead to a slightly firmer or fuller appearance for some men. P-Shot size results are usually modest, with most patients noticing improved sexual stamina and sensitivity rather than a dramatic change in size.

How much does P-Shot treatment cost, and are there other treatments to consider?

The cost of P-Shot treatment typically ranges from $1,800 to $2,400 per session, depending on the clinic and any additional services included. While the P-Shot can be a stand-alone treatment, it is sometimes combined with other treatments like hormone therapy, shockwave therapy, or lifestyle optimization for the best results.

Is the P-Shot FDA-approved?

The P-Shot itself is not FDA-approved specifically for erectile dysfunction or sexual enhancement. While off-label, many doctors consider it a low-risk, regenerative option for improving sexual health.

How long do results from the P-Shot last?

Results from the P-Shot can vary by individual. Based on patient reports and available research, some men experience benefits for several months to over a year, while others notice more gradual or shorter-term effects. Longevity often depends on age, overall health, circulation, and underlying causes of erectile dysfunction. This variability is one reason P-Shot reviews can differ widely.

Is the P-Shot safe?

The P-Shot is generally considered safe when performed by a qualified medical professional. Because it uses platelet-rich plasma derived from the patient’s own blood, the risk of allergic reaction is low. However, as with any injection-based treatment, safety depends on proper technique, sterile conditions, and appropriate patient selection.

What are the common side effects of the P-Shot?

Common side effects of the P-Shot are usually mild and temporary. These may include swelling, bruising, tenderness, or minor discomfort at the injection site. Most P-Shot negative reviews related to side effects involve short-term discomfort rather than serious complications, which remain uncommon when the procedure is performed correctly.

Who is the best candidate for the Priapus Shot?

The Priapus Shot may be best suited for men with mild to moderate erectile dysfunction, reduced sensitivity, or performance concerns who are seeking a non-surgical option. According to many Priapus Shot reviews, results tend to be more favorable for men without severe vascular disease, nerve damage, or long-standing ED.

How does the P-Shot compare to other ED treatments?

When comparing ED treatments, many men ask whether regenerative therapies offer meaningful benefits. Oral medications may provide faster, short-term results, while injections or implants are typically reserved for more severe cases. The P-Shot focuses on gradual tissue support and improved blood flow, which is why men often ask if the P-Shot is worth it compared to traditional options. In some cases, it may be used alongside other treatments rather than as a replacement.

Written By:
Kiara DeWitt, BSN, RN, CPN, Advanced Clinical Nurse Injector


Kiara DeWitt, BSN, RN, CPN founded InjectCo in early 2021 while also heading up the neurosurgery + neurology unit at Cook Children’s Pediatric Hospital as lead clinical educator. After completing her Bachelor's degree at Texas Christian University, Kiara realized just how much the aesthetic medicine industry was missing, wishing it was more focused on ethical decision-making and building relationships. Kiara’s dream was to create an atmosphere for her patients where they feel loved, empowered, and comfortable. She believes in a “lead to serve” mentality, hoping to create a more personal connection with both her patients and team alike. Kiara curated a team of 13 professionals across eight clinics, six of which are in DFW, one in Houston, and one in Austin.
Kiara loves nothing more than creating a collaborating, educational approach with her team, and thrives on personal and professional growth opportunities. She hopes that her patients feel heard and encouraged at every InjectCo visit and that they are truly excited about their personalized and well-designed aesthetic treatment plan. This love for education and safety in the industry led her to later found Texas Academy of Medical Aesthetics, an accredited training program that specializes in a 100+ hour aesthetic injector internship where students are able to train and shadow at all eight of InjectCo’s clinics.


Kiara’s patients recognize her and the entire InjectCo team as highly skilled and extremely thorough clinicians. She hopes to continue being a knowledgeable and approachable resource for clinical injectors across the country who are hoping to grow and scale their aesthetic business.

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