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Where To Inject Semaglutide For Weight Loss

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Efforts for weight loss seem endless. Even with the most effective way, you must be careful about its application on the skin. Here we are talking about the dosage of injectable semaglutide, which needs to be properly injected to avoid side effects. Let’s learn in this article how you can inject semaglutide for weight loss and the different injection sites of the body you can use.

Injection Sites To Apply Semaglutide Injections

If you want to use semaglutide injection at home, then using it properly can make a huge difference. You can take a shot under the skin of your stomach, thighs, or upper arms. Rotating the injection site is advised to avoid redness and swelling that may occur by using needles on the same site again and again. Here are some basics you must know about the injection sites:

  • The injection site must be under the skin where you can find fat.
  • You should not inject it into veins or muscles.
  • When injecting into the stomach, keep the site 2 inches away from the belly button.
  • Areas of the body that are red, brushed, or tender must not be your injection site.
  • Avoid areas having scars or stretch marks.

Considerations for Applying Semaglutide Injections

Before applying semaglutide injections to the skin of the stomach or any other part of the body, you must consider the following points:

  • Use semaglutide in a separate syringe. Do not mix it with other medications like insulin. 
  • Do not put the shots just right next to the previously used injectable site.
  • Use a new needle every time. 
  • Use the medication on the same day each week and at the same time.

Dosage of Semaglutide Injections

The dosage of semaglutide may vary depending on the patient’s health situation and adaptation of the medication by the body. The healthcare provider will start the medication with a lower amount, and once the body responds well, the dosage can be increased.

So, technically, to begin with, 0.25 milligrams (mg) is injected under the skin once a week for 4 weeks. Your doctor may increase your dose every 4 weeks. However, the dose is usually not more than 2.4 mg once a week.

How To Store The Semaglutide Injections At Home

Now that you have decided to apply the injections at home, storing them properly is equally vital. Here are a few tips:

  • Keep in a refrigerator, but do not freeze. 
  • Keep away from children. 
  • Avoid keeping outdated medicine. 
  • Ask your healthcare provider about the right way to dispose of any medicine that you do not require.
  • Store unused medicine in the original carton. 
  • Discard the used needle in a hard and closed container. 

It is advisable to ask your doctor for proper storage and disposal of medication.

Bottom Line

The application of semaglutide can give you some awesome weight loss benefits, but always keep in mind to put the injection in the right place. You can use stomach, upper arm, or thigh skin for the injections. However, you must not inject the needle in a vein or muscle. You must also consider storing the injections properly at home. Using a different needle each time is advisable to avoid any severe infections. Ask your healthcare provider to instruct you about the usage, and once you are confident, only opt for home injections.

Written By:
Kiara DeWitt, BSN, RN, CPN, Advanced Clinical Nurse Injector


Kiara DeWitt, BSN, RN, CPN founded InjectCo in early 2021 while also heading up the neurosurgery + neurology unit at Cook Children’s Pediatric Hospital as lead clinical educator. After completing her Bachelor's degree at Texas Christian University, Kiara realized just how much the aesthetic medicine industry was missing, wishing it was more focused on ethical decision-making and building relationships. Kiara’s dream was to create an atmosphere for her patients where they feel loved, empowered, and comfortable. She believes in a “lead to serve” mentality, hoping to create a more personal connection with both her patients and team alike. Kiara curated a team of 13 professionals across eight clinics, six of which are in DFW, one in Houston, and one in Austin.
Kiara loves nothing more than creating a collaborating, educational approach with her team, and thrives on personal and professional growth opportunities. She hopes that her patients feel heard and encouraged at every InjectCo visit and that they are truly excited about their personalized and well-designed aesthetic treatment plan. This love for education and safety in the industry led her to later found Texas Academy of Medical Aesthetics, an accredited training program that specializes in a 100+ hour aesthetic injector internship where students are able to train and shadow at all eight of InjectCo’s clinics.


Kiara’s patients recognize her and the entire InjectCo team as highly skilled and extremely thorough clinicians. She hopes to continue being a knowledgeable and approachable resource for clinical injectors across the country who are hoping to grow and scale their aesthetic business.

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